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Hot Topics in Neonatology Preview

Hot Topics in Neonatology TV 2019 Daily Highlights is the official news source for the Hot Topics in Neonatology 2019 Annual Meeting in National Harbor, Maryland, featuring information from leading experts in the field of Neonatology and Perinatology.

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Exposed in the Womb: Managing NAS in the NICU and Beyond

How can we better care for opiate exposed infants with neonatal abstinence syndrome? Evidence from the successful development and implementation of the “Eat, Sleep, Console” model at Yale-New Haven Children’s Hospital

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The PREMOD2 Trial: Is This the End of Umbilical Cord Milking in Newborns?

Umbilical cord milking has been regarded as a potential viable alternative to delayed cord clamping in infants who require immediate resuscitation, but how safe is this alternative means of placental transfusion?

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Lactoferrin in Preterm Infants: Do Trials Confirm It Really Doesn’t Work?

Can the administration of bovine lactoferrin to preterm neonates prevent the incidence of late-onset sepsis? Dr. Embleton reports findings from the ELFIN trial and the potential implications for future research.

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PlaNet-2 trial: Platelet Transfusion Threshold in preterm babies

Approximately 15% of preterm babies receive platelet transfusions. However, can we be certain that absolute platelet count correlates with bleeding, and do prophylactic platelet transfusions prevent or reduce bleeding?

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New Models of Care for Opioid-Exposed Infants.

Care for neonatal abstinence syndrome (NAS) remains variable. Dr. Patrick describes his experience with the design and implementation of a multicenter quality improvement collaborative for infants with NAS in improving patient outcomes.

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Management of Systemic Hypotension in Term Infants with PPHN

Systemic hypotension is a common and challenging to treat phenomenon in infants with PPHN. Dr. Lakshminrusimha discusses strategies for optimal management of systemic hypotension in this population of infants.

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Resuscitation with an Intact Umbilical Cord for Infants with Congenital Diaphragmatic Hernia

Is it feasible and safe to initiate resuscitation via intubation and mechanical ventilation prior to umbilical cord clamping in full term infants with congenital diaphragmatic hernia? Dr. Foglia presents reassuring evidence from a recent pilot trial.

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Poppi Trial: Measuring the Analgesic Efficacy of Morphine in Premature Infants

Neonatal pain is frequently undertreated and under recognized. The use of analgesic options is limited because of a scarce evidence base and limited safety profile. Dr. Slater discusses findings from the Poppi trial and future directions for research in the area of neonatal pain control.

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The Dyad affected by NAS: A Comprehensive, Developmental Approach

Neonatal abstinence syndrome (NAS) is non-homogeneous syndrome with significant long-term consequence for both the child and mother. Dr. Jannsson discusses a novel approach of understanding variable NAS expression and optimizing maternal-infant interaction.

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“Hype or Hope”: Precision Medicine in Neonatal Medicine

Precision Medicine will allow doctors and researchers to predict more accurately which treatment and prevention strategies for a particular disease will work in which groups of people. Is there a role for precision medicine in neonatology?

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Genetic Determinants of Preterm Birth

Do genetic factors play any roles in birth timing? Dr. Muglia discusses recent evidence for several genomic variations that may play a part in preterm birth. Targeting these particular genes may allow us to prevent adverse pregnancy outcomes for mothers and neonates.

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How Neighborhoods Shape Racial Disparities in Birth Outcome; Exposures to Mechanisms

To what extent could racial disparities in birth outcomes be explained by disproportionate exposure to adverse physical environments? Dr. Burris explains how intersecting social and environmental factors can account for population level health differences.

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Unanticipated Deaths of ELBW Infants in RCTs

Why do premature infants die? There is currently inadequate information on the causes and timing of death in extremely premature infants, and without identifying an appropriate causality, it will become difficult to improve our interventions.

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Trials, Tribulations and Triumphs of Team-Driven Quality Improvement

What makes a successful team-based health care system? What defines successful quality improvement practices? Dr. Buus-Frank presents her experiences from recent projects.

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Neonatology Pioneers: Avroy A. Fanaroff, MD

In this segment, “Neonatology Pioneers,” Dr. Eric Gibson and Dr. Avroy A. Fanaroff recount the early days of neonatology and the progression of advances within the field.

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Predictive Physiological Monitoring – Late Onset Sepsis

Early diagnosis of late onset neonatal sepsis remains challenging due to the complex and often nonspecific presentation of this illness. Predictive informatics for late onset sepsis may help reduce mortality by allowing for earlier and more rapid antibiotic administration.

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Anemia, Transfusion and NEC: Confusion or Causation?

There is conflicting data regarding the role of red blood cell transfusions and anemia on the development of NEC. Further studies are needed to evaluate whether preventing severe anemia is more important than minimizing RBC transfusion.

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Glucose Levels for Intervention

Transient neonatal hypoglycemia is a common phenomenon in the 48 hours after birth in healthy term infants, but how do we appropriately identify and treat those infants with severe and prolonged hypoglycemia?

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